Macon Dead, Jr., known as Milkman, grows up in "his father's money-haunted, death-haunted house with his silent sisters and strangely passive mother" and with his friend Guitar who is connected to the secret avengers called the Seven Days, falls in love with his cousin Hagar, learns from bootlegging Aunt Pilate, and then heads south, lured by the promise of buried gold and the mysteries of his heritage.